Process Supplement Platform

The fed-batch version of stirred-tank culture has become most popular at large scales. The primary driver of this trend is based on adding nutrients to a batch culture in mid-run to increase the quantity of product harvested

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•Brochure: Process Supplement Platform

The fed-batch version of stirred-tank culture has become most popular at large scales. The primary driver of this trend is based on adding nutrients to a batch culture in mid-run to increase the quantity of product harvested.

Today's experienced fed-batch bioreactor operators can expect more than 10 times the efficiencies possible from a few years ago. Yields, for some secreted recombinant protein biologicals, are now expected to be 1-3 g/L of culture, with 5-10 g/L potentially achievable. As the newest research is applied to production scale, yields exceeding 10 g/L are anticipated.

Hyclone developed a Process Supplements platform to support demand in the area of fed-batch cell culture. Each supplement is developed through the Hyclone Metabolic Pathway Design™ approach to provide specific nutrient combinations for a variety of applications, and have been successfully tested in CHO, hybridoma, NS0, HEK 293, PER.C6® (Crucell NV) and other cell lines.

Click Here To Download:
•Brochure: Process Supplement Platform