11.21.11 -- New System Will Enable 3D Cell Culture

Sponsor

In This Issue:
New System Will Enable 3D Cell Culture Managing Risks Within Platform Processes	Quality Control Of Small Molecule Pharmaceuticals 72 Prominent Personalized Medicine Products Available

Featured Articles
Managing Risks Within Platform Processes Through Media Components By SAFC A platform process is a set of standardized protocols and reagents that can be used to support a variety of clinical molecules. Typically, these protocols and reagents, including cell culture media and feeds, are standardized for a specific parental cell line such as CHO or NSO, and cell culture processes, such as batch, fed-batch, or perfusion. Platform processes prove advantageous when it comes to implementing developmental improvements.

Quality Control Of Small Molecule Pharmaceuticals Using Spectrophotometry By Thermo Scientific NanoDrop Products The control of pharmaceutical product quality is essential to ensure safe and effective use in patients. The Thermo Scientific NanoDrop 2000 Spectrophotometer offers a rapid and cost-effective method for spot-checking batch quality at various points in the pharmaceutical production line.

Spotlight On Bioreactors And Fermentors
Perfusion And Single-Use Bioreactors: A Partnership For Scale Up Perfusion has emerged as a viable technology for the commercial production of biopharmaceuticals. Perfusion solutions can offer very cost-efficient scale up solutions, driving down operating costs due to the smaller equipment and facilities needed as compared to batch or fed-batch systems.

Real-Time Respiration Measurements Many methods for measuring aerobic respiration, including electrodes and colorimetric assays, limit the capacity for obtaining replicate measurements or the ability to detect oxygen consumption in real time.

Application Note: Large Scale Cultivation Of CHO Cells In The Stirred Single-Use Bioreactor BIOSTAT® CultiBag STR The Sartorius Stedim Biotech BIOSTAT CultiBag STR is the first and only single-use bioreactor which was engineered based on the well-established principles known from classical reusable bioreactors.

Transfer And Scale-Up Of Glass Reactor Process To Single-Use Bioreactors Xcellerex provides predictive modeling and scale-up support to aid customers in determining the initial XDR bioreactor process parameters. This poster presents an example of a technology transfer from a bench-top bioreactor to Xcellerex's single-use bioreactors.

Industry News
	New System Will Enable 3D Cell Culture
	72 Prominent Personalized Medicine Products Available; A Five-Fold Increase In Five Years
	FDA Approves First Drug To Treat A Rare Bone Marrow Disease
	CureVac, Sanofi Pasteur And In-Cell-Art Collaborate On A $33.1M Project Co-Funded By The U.S. Defense Advanced Research Projects Agency
	INC Research, SAS Collaborate To Improve Clinical Trials Outcomes
	Genzyme And Cystic Fibrosis Foundation Therapeutics Announce Collaboration To Discover New CF Drugs
	New Online NeedleBuilder Streamlines Customer Selection Of Hamilton Needles
	Gilead, Tibotec To Develop And Commercialize A Single-Tablet Regimen Of Prezista With Emtriva, GS 7340 And Cobicistat
	The Microsart Disposable Funnel, An Essential For Microbiological Testing Of Samples
	BIO Strongly Supports Reauthorization Of PAHPA And BioShield Special Reserve Fund
View more headlines

Bulletin Board

DASbox: Mini Bioreactor System
The DASbox is a very compact, fully featured parallel bioreactor system. Featuring miniature bioreactors for working volumes from 60 mL to 250 mL, DASbox is perfectly suited for design of experiment (DoE) applications in cell culture, as well as microbial process development.

Featured Products And Services

Optima™ XPN Ultracentrifuge

Micro-24 MicroReactor System

• Product Details
• Download Datasheet
• Request Information

Pall Life Sciences - BioPharmaceuticals

Bioreactor And Biocontainer Vent Filters; Air, Gas Sterilizing Filters

Mobius CellReady 3L Bioreactor

WAVE Bioreactor™ 200 And 500/1000 Systems

Thermo Scientific HyClone Single-Use Bioreactor (S.U.B.)

Portable Cleanrooms

Medical-Grade Polysulfone Sanitary Couplings

Getinge 400LS And 500LS Steam Sterilizers (Autoclaves)

Mycoplasma Control Slides (M-600)

Futura Biomass Monitor

Reversed Phase HPLC Columns