Managing Risks Within Platform Processes Through Media Components By SAFC
A platform process is a set of standardized protocols and
reagents that can be used to support a variety of clinical
molecules. Typically, these protocols and reagents, including
cell culture media and feeds, are standardized for a specific
parental cell line such as CHO or NSO, and cell culture processes,
such as batch, fed-batch, or perfusion. Platform processes prove
advantageous when it comes to implementing developmental
Quality Control Of Small Molecule Pharmaceuticals Using Spectrophotometry By Thermo Scientific NanoDrop Products
The control of pharmaceutical product quality is essential to ensure safe and effective use in patients. The Thermo Scientific NanoDrop 2000 Spectrophotometer offers a rapid and cost-effective method for spot-checking batch quality at various points in the pharmaceutical production line.
Spotlight On Bioreactors And Fermentors
Perfusion And Single-Use Bioreactors: A Partnership For Scale Up
Perfusion has emerged as a viable technology for the commercial production of biopharmaceuticals. Perfusion solutions can offer very cost-efficient scale up
solutions, driving down operating costs due to the smaller equipment and facilities needed as compared to batch or fed-batch systems.
Real-Time Respiration Measurements
Many methods for measuring aerobic respiration, including electrodes and colorimetric assays, limit the capacity for obtaining replicate measurements or the ability to detect oxygen consumption in real time.
The DASbox is a very compact, fully featured parallel bioreactor system. Featuring miniature bioreactors for working volumes from 60 mL to 250 mL, DASbox is perfectly suited for design of experiment (DoE) applications in cell culture, as well as microbial process development.