Newsletter | March 21, 2012

03.21.2012 -- Navigating An Uncertain Regulatory Environment For Biotherapeutics

Bioresearch Online
Managing Data And Navigating An Uncertain Regulatory Environment For Biotherapeutics
By Tom Ricci, Pittcon Science Writer
By Tom Ricci, Pittcon Science Writer As the pharmaceutical industry pipeline continues to shift from traditional, small-molecule-based drugs to a new class of biologic therapeutics, bioresearchers need powerful bioanalytical techniques for the in-depth characterization of the protein of interest required at each developmental stage.
Read more.
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Featured Articles

Characterization Of POROS® MabCapture A™ Chromatography Media
By Christine Gebski, Suszanne Surka, Thomas Leete, et al, Applied Biosystems
As cell culture technology improvments continue to result in monoclonal antibody expression level increases, the protein manufacturing throughput bottleneck has shifted to downstream purification. Read more.

Purification Of A Monoclonal Antibody Using ReadyToProcess Columns
By GE Healthcare Life Sciences
The increasing demand for MAbs as biopharmaceuticals has promoted the development of efficient processes for cell culturing, as well as for purification. Plug-and-play units make several time-consuming steps redundant, and therefore shorten time to market. Read more.

Characterization Of Human Immunoglobulin G Binding Peptides
By Hatanaka Takaaki, Kakoi Sayaka, Ito Yuji, Kagoshima University, and Laura Moriarty, Bio-Rad Laboratories, Inc.
Human immunoglobulin G (hIgG) is a major immunoglobulin in serum that plays a central role in immune response. There is great interest in the use of hIgGs in basic biomedical research, and for the diagnosis and treatment of various diseases. Immunoglobulins (Ig) are usually purified by Protein A affinity chromatography. Read more.

Thank you for reading Bioresearch Online's Chromatography Impact. Do you have a topic you would like to see addressed in future issues, or do you have experience with chromatography that you could share? Let us know!

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