Newsletter | August 1, 2011

08.01.2011 -- Nano-Sized Drug Transporter Could Pack Big Punch

Bioresearch Online Newsletter

In This Issue:

Featured Articles

Production Of Pharmaceutical Compounds Through Microbial Fermentation
By SAFC
Microbial fermentation is the basis for the production of a wide range of pharmaceutical products, targeting practically any medical indication. Examples range from anti cancer cytotoxic drugs and vaccines, anti-infectious disease antibiotics and vaccines, to hormonal disorder therapies and many other indications.


International Variations And Similarities In Health Technology Assessment
By ICON
One of the key differences in how jurisdictions use HTA, is in how explicitly they use methods of economic evaluation to assess the value for money of new pharmaceuticals. Although the methods of cost-effective analysis in medicine had been practiced and preached over many years, it was not until the early 1980s that health systems adopted these methods as a major plank in the scientific base to support decisions regarding market access of new pharmaceuticals.

Spotlight On Purification

Datasheet: Tangential Flow Filtration Membrane Cassette Holders
These are designed for optimum performance and product recovery, Pall TFF Cassette holders are available in a variety of sizes to meet every application requirement. In this way, applications that are developed on a small system using a Centramate or Maximate cassette can be easily scaled up.


Application Note: Perfusion/Cell Retention Application
Recirculating hollow fiber systems have been used for a long time with mixed results. The recurring problem with these, and all other cell retention systems, is the difficulty in scaling up and staying sterile.


Application Note: Two-Step Purification Of Monoclonal IgG1 From CHO Cell Culture Supernatant
The increasing demand for monoclonal antibodies (MAb) as biopharmaceuticals has promoted the development of cell cultures with increased expression levels. This application note describes a two-step process for MAb purification.


Technical Brief: 'Spider' Assembly For Zeta Plus™ Filter Scale-Up
Four disposable filter configurations are currently available for Zeta Plus filter scale-up study: BC25, BC1000, BC2000, and BCE03. BC1000 and BC2000 are designed for standard Zeta Plus filter testing and BCE03 for Zeta Plus EXT Series testing.

Industry News

Nano-Sized Drug Transporter Could Pack Big Punch To Disease
Roche To Provide HIV/AIDS Tests For Early Infant Diagnosis In South Africa
Axxam And Polyphor Start Research Partnership For The Treatment Of Type-2 Diabetes
FDA Agrees With Dynavax On Consistency Of HEPLISAV™ Lots
Viamet Pharmaceuticals, NIH To Jointly Develop Novel Viamet Compound
New WHEATON Guide Highlights BioBanking Solutions
HHS Makes Plan To Improve Rules Protecting Human Research Subjects
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Reliance® 9800 Pharmaceutical Grade Washer
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