1.18.12 -- Moving From Small-Molecule To Protein-Based Drugs

With blockbuster drugs like Lipitor recently coming off patent and many others, including Plavix, heading toward the so-called "patent-cliff" as well, the pharmaceutical landscape is continuing its dramatic shift from branded drugs to generics. With such an uncertain future for traditional small-molecule drug development, pharmaceutical companies are developing a new pipeline of biologic-based drugs that potentially will fend off competition from generics.
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Tips For Achieving Great Chromatographic Results
If you're a chromatographer, then it's probably safe to say that one of your daily goals is to achieve great chromatographic results: chromatograms that feature well-resolved peaks with little-to-no band-broadening and a flat baseline — the kind of results that make your job easier and headache-free. Read more.

Efficiency Test Of ReadyToProcess™ Columns
ReadyToProcess columns are prepacked, prequalified, and presanitized process chromatography columns suited for purification of biopharmaceuticals. ReadyToProcess columns are available with several media at different volumes. Read more.

Implementation Of Nano-UHPLC System Significantly Increases Number Of Protein And Peptide Identifications
In December 2010, the Center for Experimental Bioinformatics (CEBI) at the University of Southern Denmark adopted a nano-UHPLC system in order to accelerate productivity and improve efficiencies. Implementation of the Thermo Scientific EASY-nLC 1000 instrument has increased the number of peptide and protein identifications that can be performed by the laboratory by more than 30%. Read more.

Thank you for reading Bioresearch Online's Chromatography Impact. Do you have a topic you would like to see addressed in future issues, or do you have experience with chromatography that you could share? Let us know!