Milling Technologies Used In Cell Culture Media Manufacture

Click Here To Download:
•Milling Technologies Used In Cell Culture Media Manufacture

Milling is the act of processing raw materials using machinery that grinds, compresses, or pulverizes the materials. It is a particle size reduction process. This process is achieved using a variety of machinery that applies one or more forces to refine particle sizes.

Ball Mills
Ball mills are the oldest and most common type of cell culture media mill. Ball mills can reduce material continuously or in batches and can be run wet or dry. The mill itself is composed of a horizontal cylinder with grinding media, in the form of spheres, added to aid in particle size reduction. Ceramic grinding media are used for processes that require iron– contamination-free processing, such as biopharmaceutical applications. Ball mills reduce particles through the impact of media against the mill wall as the cylinder rotates. As the media tumbles, it crushes the feed material that is caught between the mill wall and the media. Ball mills can produce particle sizes below 100 µm. With time, wear on the ceramic media spheres will occur, necessitating replacement.

Click Here To Download:
•Milling Technologies Used In Cell Culture Media Manufacture

SOURCE: SAFC