08.22.2011 -- Facilitating Scale Up-Controlled Stem Cell Cultivation

In This Issue:
Facilitating Scale Up-Controlled Stem Cell Cultivation How Biomarkers Pave Path For Drug Development	FDA Releases Plan To Foster Innovation Through Better Science First Gene-Targeted Drug For Melanoma Approved

Featured Articles
Stem Cells: Facilitating Scale Up-Controlled Stem Cell Cultivation In Stirred Suspension Bioreactors By M. Grolms, R. Olmer, U. Martin and R. Zweigerdt Stem cells have been envisioned as becoming an unlimited cell source for regenerative medicine. However, most applications require a large number of stem cells and it is difficult to translate recently applied cultivation methods into the larger scale desired.

How Biomarkers Can Pave The Critical Path For Drug Development By Robert Cote, EMD Millipore's BioPharma Services In 2004, the U.S. FDA recognized that, despite the huge increase in R&D spending and in the number of identified drug targets, submissions for new drugs and biological products had stagnated.

Spotlight On Chemical, Bulk Products, Raw Materials
White Paper: Characterization Of Hydrolysates To Enhance CHO Cell Culture Process Understanding The capacity for protein hydrolysates to exert substantial positive impact on cell growth and/or protein production in cell culture systems is well documented. Consequently, biopharmaceutical producers commonly include hydrolysates in their processes as part of a complete medium formulation or a fed-batch bioreactor system.

Flyer: Thermo Scientific HyClone Antifoam HyClone Antifoam solutions are developed to deliver 3% active Simethicone in sterile, Thermo Scientific HyClone BioProcess Container (BPC®) Systems using a validated gamma irradiation process.

Bulletin: CHT™ Ceramic Hydroxyapatite — A New Dimension In Chromatography Of Biological Molecules Hydroxyapatite chromatography was introduced in 1956, but despite numerous publications describing its merits as a unique chromatography tool, it has failed to attain the popularity of ion exchange.

Product Overview: Scandium Trifluoromethanesulfonate, Microencapsulated Scandium Trifluoromethanesulfate [Sc(OTf)3] is a water-stable Lewis Acid that is useful in many synthetic reactions.

Industry News
	FDA Releases Plan To Foster Innovation Through Better Science
	First Gene-Targeted Drug For Melanoma Approved By FDA
	Charter Medical Receives FDA 510(k) Clearance For Next-Gen Cryogenic Stem Cell Storage Containers
	Kimble Chase Introduces KIMAX Storage/Media Bottles
	GE Healthcare To Acquire PAA Laboratories GmbH
	Spinnovation CEO To Discuss NMR-Based Methods For Bioprocess Optimization
	BioTek Presents New Products, Posters At 2011 ELRIG Drug Discovery Conference
	Pittsburgh Researchers Combine Viscotek GPC And Zetasizer Nano In Work On Novel Polymers For Drug Delivery
	Discuss The Effect Of Humidity On Powders With Freeman Technology At Powtech 2011
	ICON Acquires Firecrest Clinical To Enhance Investigator Site Performance
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Featured Multimedia

Video: NanoDrop Microvolume Quantitation Of Nucleic Acids
The NanoDrop microvolume sample retention system functions by combining fiber optic technology and natural surface tension properties to capture and retain minute amounts of sample independent of traditional containment apparatus such as cuvettes or capillaries.

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