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Sartobind® STIC membranes are a new group of Salt Tolerant Interaction Chromatography membrane adsorbers. They bind negatively charged impurities such as viruses, DNA, and HCP at much higher salt concentrations than Q matrices. Sartobind® STIC membranes eliminate the need for feedstream dilution before flowthrough polishing of therapeutic proteins and mabs. The single-use product reduces validation cost, consumption of buffers, footprint, and speeds up time to market. www.sartorius-stedim.com/sartobind
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Featured Articles
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Clarifying The Status Of Extractables And Leachables
By Weibing Ding and Jerold Martin, Pall Life Sciences
There are many reasons why pharmaceutical manufacturers may either embrace the concept of single-use manufacturing or reject it. One concern that is often raised regardless of application is the issue of extractables and leachables.
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LIMS Streamlines Translational Science
By Trish Meek, Director of Life Science Strategy, Informatics at Thermo Fisher Scientific
In translation science, organizations are utilizing laboratory information management systems (LIMS) to facilitate collaboration and manage experimental results of clinical outcomes.
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Now in its 14th year, TIDES® continues to build upon its reputation as the place to meet all the important players in the oligonucleotide and peptide therapeutics industries, from discovery all the way through manufacturing. Attendees will have access to all four conference tracks:
• Oligonucleotide and Peptide Manufacturing Technology and Product Development
• Oligonucleotide Therapeutics Discovery
• Nucleic Acids Technologies for Molecular Diagnostics
• Peptide Discovery and Development
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Spotlight On Purification
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SteriLUX® Filters Brochure
The hydrophilic SteriLUX polyvinylidene fluoride (PVDF) membrane filter is available in discs, capsules, high-capacity UltraCap® and UltraCap® H.D. capsules, and cartridges with 0.1 µm, 0.2 µm, 0.4 µm, and 0.6 µm absolute ratings.
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Product Sheet: HFC39 Series Couplings — Medical-Grade Polysulfone, 1/4", 3/8", And 1/2" ID
HFC39 couplings feature automatic shutoff valves and offer a cost-effective replacement for expensive, heavy, stainless steel connectors or fittings. HFC medical-grade polysulfone meets the most stringent requirements, such as USP Class VI, MEM elution, agarose overlay, hemolysis in vitro, and USP physicochemical tests.
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MODcol® MultiPacker® And Spring® Column Packing Guide
Because it employs a pneumatic packing mechanism, the MultiPacker instrument for 25-mm and 50-mm spring columns uses no electrical power, making it safe for work with many types of solvents and a good column for hazardous environments.
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Automated, Single-Use Purification Platforms In Biopharmaceutical Production
The use of disposable bioreactors and single-use purification platforms for normal flow filtration (NFF), tangetial flow filtration(TFF) and preparative chromatography have received significant attention in years. Up until very recently, the use of single-use purification platforms was limited almost exclusively to manually operated systems.
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Featured Multimedia
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| Stax™ Depth Filter Systems Video |
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With simplicity, intuitive operation, safety, and speed, Stax depth filter systems are ideally suited for the most demanding prefiltration, clarification, and adsorption applications in the biopharmaceutical industry.
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Industry Webinar
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| Bio-G Webinar: Quality By Design — An Industry Perspective |
March 28, 2012
1:00 PM PST, 4:00 PM EST
3:00 PM GMT, 4:00 PM CET
In this 60-minute webinar and Q & A session two panelists, Jim Lambert from Genentech and Rick Johnston, Ph.D., from Bio-G, will present their perspectives on Quality by Design (QbD), and answer questions about the implementation of QbD in biopharmaceutical manufacturing.
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