Application Note | July 27, 2005
Characterization Of Mixed Micelles
Source: Malvern Instruments
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•Application Note: Characterization Of Mixed Micelles
Ionic-nonionic surfactant mixtures have been characterized quite well using a variety of techniques individually and in combination over the last decade. Interest in these surfactant systems stems from a broad application base. These surfactant systems, or "detergents" have found application in oil recovery due to enhanced solubility, higher cloud points, and lower Krafft points than the corresponding pure surfactant in solution.1 The cosmetics industry found mixed surfactant systems caused less damage to corneal and epithelial tissues.2 Surfactants form micelles in solution in which the ionic/nonionic head group is exposed and the hydrophobic tail is buried, and co-micellization takes place in mixed systems. Micelle size is an important parameter which correlates with solubilizing efficiency and critical micelle concentration. In this report, the Malvern instruments Zetasizer Nano ZS is used to measure micelle size for TX-100/SDS, the most studied nonionic/anionic micelle system, at a variety of ionic strengths and surfactant compositions.
•Application Note: Characterization Of Mixed Micelles
•Application Note: Characterization Of Mixed Micelles
Ionic-nonionic surfactant mixtures have been characterized quite well using a variety of techniques individually and in combination over the last decade. Interest in these surfactant systems stems from a broad application base. These surfactant systems, or "detergents" have found application in oil recovery due to enhanced solubility, higher cloud points, and lower Krafft points than the corresponding pure surfactant in solution.1 The cosmetics industry found mixed surfactant systems caused less damage to corneal and epithelial tissues.2 Surfactants form micelles in solution in which the ionic/nonionic head group is exposed and the hydrophobic tail is buried, and co-micellization takes place in mixed systems. Micelle size is an important parameter which correlates with solubilizing efficiency and critical micelle concentration. In this report, the Malvern instruments Zetasizer Nano ZS is used to measure micelle size for TX-100/SDS, the most studied nonionic/anionic micelle system, at a variety of ionic strengths and surfactant compositions.
In order to verify the performance of the Zetasizer Nano ZS, a comparison to reference data from a previous study was conducted. The reference data was produced utilizing the following methods. Triton X-100 (polyoxyethylene p-t-octylphenol, Rohm and Haas Co., Philadelphia, PA) and sodium dodecyl sulfate (SDS,"Puriss" grade, Fluka Chemical Corp., Haupauge, NY) were used with no further purification. Stock solutions of 100mM SDS/TX-100 were prepared in NaCl solutions of various ionic strengths. Micelle solutions were filtered and analyzed by size exclusion chromatography (SEC). Fractions were collected from SEC eluent for subsequent micelle size determination by dynamic light scattering (DLS).
SOURCE: Malvern Instruments
Click Here To Download:
•Application Note: Characterization Of Mixed Micelles