Advantages Of Oxygen Control In CO2 Incubation For Research And Clinical Applications
By Ted Andrew, Product Manager
New Brunswick Scientific
Physiological in vivo oxygen concentrations can range from 1% to13%, yet most research and culture is done at ambient 21% O2. Studies have shown dramatic differences in gene expression profiles and phenotypic changes in the cells between these conditions. Scientists in a variety of emerging fields are coming to understand the value of O2 control in addition to CO2 and temperature control in their daily applications. New Brunswick Scientific’s (NBS’s) CO2 Incubators are offered with three levels of oxygen control. The most popular is the 1–19% option for hypoxic studies. For more stringent requirements, there is a 0.1–19% option. Lastly, for a more robust application dynamic, NBS offers a 1–95% control for both hypoxic and hyperoxic tri-gas control (CO2, N2, and O2).
BioTechniques Protocol Guide 2009 (p. 15) doi 10.2144/000113035