Newsletter | July 6, 2011

07.06.2011 -- A Guide To Homogenization For Biotech And Pharma

Bioresearch Online Newsletter

In This Issue:

Featured Articles

A Guide To Homogenization in the Pharma, Biotech, And Cosmetic Industries
By GEA Niro Soavi
High-pressure homogenization in the pharmaceutical industry has proven its ability to make more stable product, with better active ingredient dispersion, than has been achieved with conventional stirrers, rotorstator devices, or colloid mills.


Helpful Hints For Better Aseptic Technique
By Bionique Testing Laboratories
Developing successful aseptic techniques requires specific training and a clear understanding of the nature, types, and potential sources of contamination. Freshney (2005) and Ryan (2008a) provide good information on these critical areas. The following recommendations are designed to help improve your aseptic techniques and to preserve the integrity of your cell cultures.

Spotlight On Clinical Trials

Article: Health Technology Assessment Adds Value To All Phases Of Drug Discovery And Clinical Development
The most effective way to use health technology assessment to maximize market access is to start early and update often. This article outlines the way in which economic thinking and the early application of health technology assessment can add value to all phases of drug discovery and clinical development.

Article: Health Technology Assessment Adds Value To All Phases Of Drug Discovery And Clinical Development

Article: Controls For Photometric Tests — Implications For Low Capacity Test Systems
Instrumentation for photometric endotoxin tests must have a capacity for at least 12 samples in order to meet the requirements of the pharmacopeial endotoxins test chapters. Small test systems with a low capacity, including those that rely on archived curves, cannot accommodate the controls specified in the pharmacopeia or guidance documents.

Article: Controls For Photometric Tests — Implications For Low Capacity Test Systems

Application Note: The MIQE Guidelines And Assessment Of Nucleic Acids Prior To qPCR And RT-qPCR
Quantitative PCR has emerged as a fundamental technique in molecular and clinical diagnostics. Before now, little or no standardization in reporting existed, and as a result, experiments were frequently hard to replicate. In addition, many assumptions upon which the technique depends, in particular those pertaining to reference gene stability and amplification efficiency, were often, in fact, invalid.

Application Note: The MIQE Guidelines And Assessment Of Nucleic Acids Prior To qPCR And RT-qPCR

Datasheet: Thermo Scientific Informatics Services
To support customers worldwide, Thermo Scientific Informatics Services offers comprehensive professional services ranging from implementation and validation to support, training, and education.

Datasheet: Thermo Scientific Informatics Services

Industry News

Aptar Pharma's Nasal Spray Device Chosen For Pain Management
Results From Phase 2 Study Of Axomadol In Chronic Low Back Pain
New Pinch Valve From Emerson Now Allows Automated Control Of Low Volume, Clean, And Sterile Liquids
Thermo Fisher Scientific Uses Nandrop Instrumentation For Microvolume Quantification of Nucleic Acids
Phase III Study Shows Once-Daily NVA237 Is Superior To Placebo In Improving Lung Function In COPD
Sorbent Therapeutics Completes $36M Series B Financing
Chromatrap Technology Assists Development Of State-Of-The-Art Pediatric Healthcare
Sistemic Ltd Announces Companion Biomarker Program
Lonza's New GS System Medium And Feed Platform Reaches 10g/L
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Featured Multimedia

Podcast: The iPad In Clinical Trials Part 1
Podcast: The iPad In Clinical Trials Part 1
Dr. Colin Miller, senior vice president, medical affairs, at BioClinica, discusses the benefits of the iPad and other tablet devices in clinical trials.

Featured Products And Services

Pharmaceutical Clinical Packaging
Pharmaceutical Clinical Packaging

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Patheon Inc.

Clinical Trial Management Software
Clinical Trial Management Software

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Sparta Systems, Inc.

XDR™ Single-Use Bioreactor
XDR™ Single-Use Bioreactor

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Xcellerex

Virtis Ultra Lyophilizer
Virtis Ultra Lyophilizer

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SP Scientific

Mycoplasma Test Services
Mycoplasma Test Services

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Bionique Testing Laboratories, Inc.

TruTorr Single-Use Sensor
TruTorr Single-Use Sensor

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Finesse Solutions, LLC

Steam Sterilizable Solutions: Dissolved Oxygen, pH, And Conductivity
Steam Sterilizable Solutions: Dissolved Oxygen, pH, And Conductivity

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Emerson Process Management, Rosemount Analytical

NEWMIX™ C-Mix™ Bags
NEWMIX™ C-Mix™ Bags

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ATMI LifeSciences

MPU Series Couplings: Medical-Grade Polysulfone, 3/4" ID
MPU Series Couplings: Medical-Grade Polysulfone, 3/4" ID

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Colder Products Company

Thermo Scientific HyClone Serum-Free Media
Thermo Scientific HyClone Serum-Free Media

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Thermo Scientific HyClone

Custom Pharmaceutical Vessels And Tanks
Custom Pharmaceutical Vessels And Tanks

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Walker Barrier Systems

Baumann 85000 Sanitary Pinch Valve
Baumann 85000 Sanitary Pinch Valve

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Emerson Process Management, Fisher Valve