Scientists Find Protein That Promotes Cancers, Heart Disease; Create Substance To Block Its Effects

Strong scientific evidence suggests that high levels of a blood protein called galectin-3 may increase the risk of heart attacks, cancer and other diseases, and help forecast the outcome of those diseases, a scientist reported here recently at the 244th National Meeting & Exposition of the American Chemical Society, the world’s largest scientific society.

Isaac Eliaz, M.D., who outlined the scientific case against galectin-3, said a new galectin-3 blood test approved by the U.S. Food and Drug Administration can be useful in determining the risk and prognosis of numerous diseases. His presentation also included evidence that modified citrus pectin, produced from the white pulp inside orange peel and other citrus fruit, can bind and block excess galectin-3 activity.

The body cannot absorb natural citrus pectin, which passes through the GI tract undigested, Eliaz explained. Modification permits its absorption into the blood, where it blocks the negative effects of galectin-3, he added.

Eliaz said his conclusions were based on evidence from clinical trials involving close to 8,000 people.

About American Chemical Society
The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 164,000 members, ACS is the world’s largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.