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ProteOn XPR36™: Antibody Screening & Small Molecule Screening

Learn more about how other researchers are accomplishing antibody screening and small molecule screening on the ProteOn XPR36.
Details

Click Here To Download:
Rapid Assay Development And Optimization For Small Molecule Drug Discovery
Webinar Series: Become An SPR Expert
Intro to the ProteOn XPR36 Surface Plasmon Resonance (SPR) Interaction System
Pushing The ProteOn SPR System To Its Limits

The ProteOn system and its novel 6 x 6 interaction array meets the challenge of high throughput label-free interaction analysis, providing solutions for both rapid experimental optimization and high throughput screening. In doing so, Bio-Rad has transformed the label-free screening workflow from repetitive serial injections, allowing you to reach better informed research conclusions first, with data you can confidently trust, and the flexibility to design and execute experiments without limitations.

Antibody Screening
The ProteOn system's One-Shot Kinetics approach facilitates the rapid screening of antibodies or antibody-binding targets that exhibit the optimal binding characteristics for particular applications. High-quality data is generated by automatically correcting for baseline drift using a unique real-time injection reference on functionalized surfaces such as anti-Fc Ab or protein A/G [1]. By functionalizing a single ProteOn sensor chip with 36 unique target proteins, information-rich kinetic screening data can be acquired in a high-throughput fashion.

Small Molecule Screening
Combining high-quality kinetic data and high-throughput capabilities on the ProteOn system results in a powerful tool for small molecule screening. The ProteOn system's simultaneous, real-time referencing results in a highly stable baseline that enables accurate detection of small molecule interactions. Binding kinetics for molecules as small as 95 Da are obtained using the ProteOn GLH sensor chip, the first super high density sensor chip specifically designed for small molecule detection and kinetic measurements.

Click Here To Download:
Rapid Assay Development And Optimization For Small Molecule Drug Discovery
Webinar Series: Become An SPR Expert
Intro to the ProteOn XPR36 Surface Plasmon Resonance (SPR) Interaction System
Pushing The ProteOn SPR System To Its Limits


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Bio-Rad Laboratories, Inc.

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