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Zinc Fingers Point The Way
January 9, 2011
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•Article: Zinc Fingers Point The Way
•Article: Zinc Fingers Point The Way
•Article: Zinc Fingers Point The Way
By Kevin Kayser, SAFC
The field of targeted genome editing has advanced rapidly since the recent advent of Zinc Finger Nuclease (or ZFN) technology. ZFNs are custom-engineered fusion proteins that bind DNA in a targeted manner, creating double-stranded breaks at precise locations, which enable insertions, deletions, or modifications of the genome. The result is a reliable method for creating genetically modified cell lines and model animals that is both faster and more accurate than traditional methods.
Used with permission from Life Science Leader magazine.
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