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Pall's ultrafiltration centrifugal devices simplify many common nucleic acid and protein handling procedures. These devices provide efficient concentration and salt removal of samples from 50 µL to 60 mL in just minutes.

Pall's microfiltration centrifugal devices are used in separation and small-scale general filtration procedures. These devices can be used in combination with chromatography resins to create a fast, efficient method for purifying proteins of interest.

Pall's Centrifugal Devices Feature:

• Rapid processing: Achieve high recoveries (typically greater than 90%) in as little as five to ten minutes.
• High performance membranes: Omega™ polyethersulfone ultrafiltration membrane provides higher flow rates and is lower protein binding than competitive membranes. This results in lower processing time and the highest possible recoveries.
• Low protein binding: Devices are constructed of low-binding polypropylene to maximize sample recovery.
• Variety of MWCO's and pore sizes: Available with low-binding microfiltration membranes for particulate removal or chromatography separations. Also available with ultrafiltration membrane for rapid concentrating and/or desalting of proteins.
• Easy to use: Once you have identified the right MWCO or pore size ranging from 1 kD to 0.45 µm, the devices are color-coded for easy visual identification.
• Ideal for fast batch mode chromatography applications: Nanosep® centrifugal devices with microfiltration membrane serve as a perfect housing for chromatography resin. The spin device can be filled with the resin of choice to perform the desired protein purification application.

Typical Applications for Centrifugal Devices

• Protein or nucleic acid sample concentration
• Desalting/buffer exchange
• Purification from acrylamide gels
• Clean-up of labeling and PCR reactions
• Removal of free nucleotides
• Virus concentration or removal
• Sample prep prior to HPLC