Application Note

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The absorption of a nasal spray, as with many other pharmaceutical sprays, is dependent on how well it remains on the affected area of skin. Research has indicated* that addition of thickeners such as microcrystalline methoxy cellulose or dispersed cellulose can dramatically increase the efficacy of the spray, as they impart a higher low shear rate viscosity. A large diameter cone was used for the measurements to enhance sensitivity at low stress, as in this case the low stresses more closely simulate the application.

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