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The Aber Biomass Monitor is widely recognized as the standard in on-line instrumentation for viable biomass measurement and has been designed to meet GAMP4 requirements. It enables real time, accurate measurement of the biomass in bioreactors at both laboratory and industrial scale. The combination with Applikon's ez-Control process control system offers the unique possibility to accurately control the biomass concentration in the bioreactor. Backed by a dedicated support team and an international distributor network, it's easy to see why the world's leading company in biomass measurement systems and the market leader in laboratory scale bioreactor systems for cell culture have teamed up to offer this unique technology to the global cell culture R&D community.

The unique probe suitable for cGMP applies a radio frequency field to the biomass in a bioreactor. The output is an accurate measurement of the concentration of viable cells. The Aber Biomass Monitor system is responsive to viable cells and is insensitive to cells with leaky membranes, the media, gas bubbles and debris.

By integrating the Biomass sensor into the ez-Control process controller Applikon is the first company worldwide to offer a process controller that accurately controls pH, Temperature, Dissolved Oxygen, Foam/Level, Agitation and Viable Biomass. The BioXpert SCADA software further enhances the capabilities of the system by offering 21 CFR part11 support, allowing the system to be operated in a validated cGMP environment.

SOURCE: Applikon Biotechnology