Article
A Single-Use Bioreactor For Both Cell And Microbial Cultures: A Dream Becomes Reality
February 2, 2012
By Nico M.G. Oosterhuis, Frank H. van Dongen, CELLution Biotech BV
Application of single-use equipment is common practice in the biopharmaceutical industrial and academic field. Compared to the traditional glass or stainless steel bioreactors, single-use bioreactors offer clear advantages: a quicker turnaround time; minimal utilities required; greatly reduced risk of cross contamination; more operational flexibility; reduced validation requirements. However, until recently, single-use bioreactors could only be used for animal cell cultures, due to limitations in mixing and mass-transfer.
As single-use technology not only has significant benefits for cell culture processes, but clearly also for microbial fermentation processes and for seed-trains, process development and small scale production, there is a strong need for singleuse bioreactors supporting more demanding bioprocesses.
The content you requested is only available to registered users of Bioresearch Online. By registering now, you'll get exclusive access to this piece of content and thousands of addtional articles and product reviews across our entire network of sites.
