| Datasheet: HAAKE EZ Cool 80 Circulator |
The economical, easy-to-use HAAKE EZ Cool 80 Circulator features a bathless design that minimizes fluid evaporation. |
05/19/2008 |
192.5 KB |
| Article: Advances In Separation And Purification: Purifying Monoclonal Antibodies |
The affinity capture paradigm that dominates industrial IgG purification has proven unsuitable for IgMs because, in most cases, they are affected adversely by harsh elution conditions. The large size of IgMs also a challenge because it limits the operating conditions and performance of traditional porous-particle-based chromatography media. This article describes how these challenges can be overcome with available technology to develop effective manufacturing procedures for IgM monoclonal antibodies. |
05/16/2008 |
904.3 KB |
| Application Note: Harvesting Cells From Corning® CellSTACK® Culture Chambers |
Harvesting cells from multilayer
CellSTACK culture chambers that do
not allow direct pipette access to the
cells can be challenging. The inability
to view the cells microscopically adds to
this challenge. |
05/15/2008 |
296.0 KB |
| Application Note: Superior Growth Of MDBK Cells In Corning® CellSTACK®-40 Culture Chambers Under Actively Gassed Conditions |
Recently, we reported the enhanced performance and increased yields of Madin-Darby
Bovine Kidney (MDBK) cells in CellSTACK-40 Culture Chambers relative to a similar
competitor product (Superior Growth of MDBK Cells in Corning CellSTACK-40 Culture
Chambers, Corning publication no. CLS-AN-054). |
05/15/2008 |
304.8 KB |
| Application Note: Superior Growth Of MDBK Cells In Corning® CellSTACK™-40 Culture Chambers |
Large-scale culture of adherent cells, such as for animal vaccine production, has often
required using large numbers of roller bottles. Processing the cells in these bottles is very
labor intensive. Corning has developed a scalable culture vessel system, referred to as
CellSTACK Culture Chambers, for culturing larger quantities of adherent cells. |
05/15/2008 |
186.3 KB |
| Application Note: A Cost Effective, Scalable Method For Transfections In Corning® CellSTACK® Culture Chambers |
The ability to produce milligram amounts of engineered proteins in a rapid and cost
efficient manner is highly desirable. However, the high cost of lipid-based transfection
reagents, the popular method of choice, makes large scale transfections cost prohibitive. |
05/15/2008 |
273.4 KB |
| Technical Bulletin: Growing More Cells: A Simple Guide To Small Volume Cell Culture Scale-Up |
We need more cells… Life science researchers
are constantly being challenged to produce more
cells for cell-based experiments and assays, or for
producing recombinant proteins, antibodies and
viral vectors. |
05/15/2008 |
442.4 KB |
| Technical Bulletin: Corning Guide For Identifying And Correcting Common Cell Growth Problems |
Although very popular among life science
researchers, cell culture can be a very difficult
tool to work with in the laboratory. Unlike other
common laboratory tools such as electrophoresis
or chromatography, cell culture makes dynamic,
ongoing use of living organisms. |
05/15/2008 |
1.99 MB |
| Technical Bulletin: Understanding And Managing Cell Culture Contamination |
No cell culture problem is as universal as that of
culture loss due to contamination. All cell culture
laboratories and cell culture workers have experienced
it. Culture contaminants may be biological
or chemical, seen or unseen, destructive or seemingly
benign, but in all cases they adversely affect
both the use of your cell cultures and the quality
of your research. Contamination problems can be
divided into three classes. |
05/15/2008 |
413.1 KB |
| Poster: Disposable Large Volume Spinner Flasks Provide Versatile And Economical Options For Scale-Up Of Suspension Cell Cultures |
Suspension cell culture in large scale production is increasingly
being integrated into drug discovery campaigns, and suitable scale
up vessels for suspension growth are evolving to keep pace.
Historically, either disposable plastic shaker flasks or glass spinner
vessels have been used for such culturing. |
05/15/2008 |
56.5 KB |
| Flyer: Flow Cytometry Products |
Preserve valuable samples for up to 7 days by eliminating adverse affects of time, storage
and transport conditions on sample integrity. |
05/15/2008 |
320.4 KB |
| Poster: Cyto-Chex® Blood Collection Tube Stabilizes Samples Stored At Elevated Temperatures For Flow Cytometry Analysis |
We have previously demonstrated that Streck Cyto-Chex® Blood Collection Tube
(BCT) preserves whole blood specimens for HIV testing by flow cytometric
analysis for seven days at room temperature. Increased stability reduces the
need for weekend staffing and shipping delays are not likely to require patient
redraws. |
05/15/2008 |
313.6 KB |
| Poster: Stabilization Of White Blood Cells And Immunologic Markers For Extended Analysis Using Flow Cytometry |
Accurate and reliable measures of CD4+ T
lymphocytes (CD4+ T cells) are essential for the evaluation and
management of human immunodeficiency virus (HIV)-infected
persons. Transportation to a laboratory capable of these
analyses in a timely fashion may be difficult to accomplish,
especially in resource-poor settings. |
05/15/2008 |
175.3 KB |
| Application Note: Cyto-Chex® BCT™ Allows For Accurate T-Cell Counts By Flow Cytometry 14 Days Post Sample Collection |
The goal of this study was to demonstrate that whole blood
specimens collected in Streck Cyto-Chex® Blood Collection
Tube (BCT) are preserved at room temperature for
HIV testing by flow cytometry for a period beyond seven
days. |
05/15/2008 |
313.6 KB |
| Application Note: Blood Specimens Stable In Cyto-Chex® BCT™ At Elevated Temperatures |
The purpose of this study was to examine the effect of elevated
temperatures on blood samples collected and stabilized
in Cyto-Chex BCT. The data presented in this report
demonstrate that while K2EDTA samples consistently fail
to maintain clear lymphocyte separation at elevated temperatures, Cyto-Chex BCT stabilizes CD3, CD4 and CD8
for seven days at 30°C. |
05/15/2008 |
828.0 KB |
| Application Note: Cyto-Chex BCT Stabilizes Light Scatter And Cell Morphology |
The purpose of this study was to compare light scatter
data generated by flow cytometry and cell morphology
detail obtained by blood smears from samples collected
into Cyto-Chex BCT and K2EDTA blood collection
tubes. |
05/15/2008 |
589.5 KB |
| Application Note: Cyto-ChexBCT Stabilizes Whole Blood For Seven Days For Immunophenotyping By Flow Cytometry |
The purpose of this study was to compare data generated by flow cytometry from blood samples collected in Cyto-Chex Blood Collection Tubes (BCT) and stored for seven days to the data from blood samples from the same donors collected in K3EDTA tubes analyzed at six hours. |
05/15/2008 |
384.3 KB |
| User Guide: Corning® CellSTACK Culture Chambers |
CellSTACK Culture Chambers are the newest
addition to Corning Life Sciences’ line of reliable
and fully tested cell culture products |
05/15/2008 |
490.1 KB |
| Brochure: Corning® CellSTACK Culture Chambers |
The Corning CellSTACK Culture Chambers are the newest addition
to Corning Life Sciences line of reliable and fully tested cell culture
products. Whether your cells grow attached or in suspension, Corning
has cell culture scale-up products that will meet your requirements. |
05/15/2008 |
596.7 KB |
| Corning® Roller Bottles Selection and Use Guide |
Corning plastic roller bottles are manufactured from virgin polystyrene and feature one-piece
seamless construction. The caps are manufactured from virgin, high-density polyethylene
and are free of heavy metals. Both plastics meet the USP Class VI requirements for plastic
containers and closures. |
05/15/2008 |
403.8 KB |
| Brochure: Corning® Polycarbonate Erlenmeyer and Fernbach Flasks |
Corning baffled and plain Erlenmeyer and Fernbach culture
flasks are ideal for shaker culture applications and storage.
Like all Corning flasks, the Erlenmeyer flasks are certified
nonpyrogenic and sterile. |
05/15/2008 |
246.7 KB |
| Datasheet: Corning® Polycarbonate Erlenmeyer and Fernbach Flasks |
Corning baffled and plain Erlenmeyer and Fernbach culture
flasks are ideal for shaker culture applications and storage.
Like all Corning flasks, the Erlenmeyer flasks are certified
nonpyrogenic and sterile. |
05/15/2008 |
209.8 KB |
| Flyer: 1L & 3L Disposable Spinner Flasks |
Completely Disposable Spinner Flasks arrive “Ready-to-Use” – Fully
assembled, sterilized by gamma radiation, and certified nonpyrogenic. |
05/14/2008 |
148.3 KB |
| Datasheet: Corning® Disposable Spinner Flasks |
The Corning disposable spinner flask
system comes ready-to-use with paddle and
integrated magnet, eliminating the need for
time-consuming assembly or cleaning and
reassembly. |
05/14/2008 |
251.6 KB |
| Datasheet: Corning® 1L and 3L Disposable Spinner Flasks |
The Corning disposable 1L and 3L
spinner flasks come ready-to-use
with paddle and integrated magnet,
eliminating the need for timeconsuming
assembly or cleaning
and reassembly. |
05/14/2008 |
205.4 KB |
