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RSSSingle-Use Bioreactors: A Brief Review Of Current Technology
November 19, 2009
•Feature Article: Single-Use Bioreactors: A Brief Review Of Current Technology
By Cheryl Scott
Say "disposable bioreactor," and whoever you're talking to is most likely going to picture a plastic bag on a rocking platform. In fact, I remember back in late 1999, as associate editor for another magazine, when I copyedited one of the early papers that described the Wave bioreactor (1). Even that early in my career as a technical editor, when my understanding of the industry was over six years younger than it is now, I recognized the thing for what it was: a potential revolution in biopharmaceutical production.
Since then, it has become an established and accepted addition to the biotechnological toolbox, having proven itself in published studies from Chiron Corporation, IDEC Pharmaceuticals, Introgen Therapeutics Inc., Lonza Biologics, the Massachusetts Institute of Technology, Merck Research Laboratories, Novartis, and Schering- Plough Research Institute, among others (2). However, although it may have been the first name in disposable bioproduction, the Wave bioreactor is far from the last word in this growing field.
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