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•New Platform For Producing Viral Vaccines

EB14 Suspension Cell Line Adapted to Serum-Free Media

Coleen McCormick, Ph.D., and Majid Mehtali, Ph.D.

Many human and animal vaccines currently being developed are produced in eggs or primary chicken embryonic fibroblasts (CEFs). Eggs and CEFs are used to manufacture both human and animal health vaccines (Table 1). These processes have changed little in more than 60 years.

There are, however, known limitations to these platforms, including the time and effort involved in the manufacturing process, the number of fertilized eggs required, the potential for allergic reactions to eggs, and the inability to grow viruses that are lethal to eggs or chickens.

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•New Platform For Producing Viral Vaccines

SOURCE: SAFC