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DASGIP has launched two new gassing systems to address needs of pilot scale and in industrial biotechnology.

DASGIP's new MX4/1 provides mass flow controlled gas mixture of carbon dioxide, oxygen, nitrogen and air with flow rates up to 30 sL/min in one channel for single vessel operation. This high flow gassing module allows microbial and especially cell culture application up to pilot scale.

With the MX4/1 and the MX4/4, serving four vessels, customers can adjust their gassing system to specific inlet gasses such as artificial air (e.g. 90% oxygen, 10% nitrogen) to use gas mixtures according to their security standards.

When some processes require unconventional gasses such as the use of methane and carbon monoxide in biofuel development, the new DASGIP MF4 is the perfect solution. MF4 provides mass flow controlled gassing up to 30sL/min for four parallel channels and users are free to select any four input gasses to suit their needs. Separate channels allow even supply of reactive gasses with the same module. Industrial mass flow controllers and individual set points for each inlet gas make sure an accurate suply. Flow rates up 30 sL/min enable users working at pilot scale. The four separate channels allow the supply of even reactive gases with one module.

CSO Dr. Matthias Arnold points out the optional pressure sensors of both gas mixing systems and the MF4: "They allow safe operations of glass vessels and even bags. Together with further features such as check valves against back flush of liquids save and efficient processes in R&D and production are guaranteed".

DASGIP's series of gassing solutions now cover a wide range of needs in different applications such as cell culture, microbial fermentation and biofuel development. The product range includes the popular MX4/4 supplying independently blended gas mixture in four parallel channels, as well as the 2006 introduced rotameter-based gassing system RX2/4.

RX2/4 utilizes four rotameters and flow valves at each outlet allow manual flow control. Mixing valves for each reactor guarantee well-coordinated supply of two input gasses such as air and oxygen when using the. Users looking for either oxygen enrichment in microbial fermentation or application in biorenewables at bench top scale benefit from this economical gassing solution.

System integration is an outstanding advantage of using DASGIP modules: not only is every DASGIP modules a tried and tested component of the DASGIP Parallel Bioreactor Systems, they can also be operated as stand alone modules with other equipment and bioreactors. Furthermore, DASGIP provides digital and analog interfaces to allow perfect integration into third-party control systems. DASGIP systems directly address the important industry programs such as the FDA's ‘Quality by Design' approach and PAT initiative.

SOURCE: DASGIP AG