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06.24.2009 -- New ADHD Genes Found: Could It Guide Researchers To Better Drug Targets?

June 24, 2009

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Featured Articles
The Case For 'Good Storage Practice' In Biopharmaceutical Development
By F. John Mills, Oscar Moralez, and Jennifer Benner, BioProcess International
Those working in medical research and drug development have always needed to store biological materials such as blood samples and active pharmaceutical ingredients. Stored biomaterials can be used for a number of purposes, from medical education to examination of disease processes over time.
Read the complete article.

A Bioassay Glossary
By Robert Singer, David M. Lansky, and Walter W. Hauck, BioProcess International
In the biopharmaceutical industry, white papers, standards, and regulatory documents are often published in draft form to elicit comments from the industry over a designed review period.
Read the complete article.

Top News Stories
ADHD Genes Found; Known To Play Roles In Neurodevelopment
GSK, Chroma Therapeutics In $1B Deal To Develop Novel Macrophage-Targeted Drugs
SP Industries Freeze Drying Sample Extractor Ensures Effective Cycle Development
Cutting Edge Study Examines Autoimmune Drugs, Classes, And Market-Leading Companies
Cancer Researchers Develop Model That May Help Identify Cancer Stem Cells
Vaccines From The Bioreactor: Bioprocess Increases Vaccine Yield
NIH Expands Human Microbiome Project
NextDocs DIA Reference Model Supports Faster Life Sciences Compliance
Biomodels' Oral Mucositis Expertise Speeds FDA Approval For ActoGeniX's Phase 1b Trial Of AGO13 In Cancer Patients
New BioFlux 1000 Workstation Enables High-Throughput, High-Content Cellular Assays
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The CellGard Energy Saver (ES) NU-480 Biological Safety Cabinet (BSC) is now available in North America. The CellGard ES Biological Safety Cabinet is a Class II, Type A2 BSC which features the exclusive NuAire TouchLink LCD Control Center, a DC-ECM motor, sloped window, and the longest filter life in its class. Download the product brochure for more information.

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Application Note: When To Replace Your Biological Safety Cabinet
Use of modern day biological safety cabinets (BSCs) began in the early 1970s with BSCs that were manufactured to the NIH-03-112C Standard and subsequently the NSF Standard 49. BSCs manufactured in the 70s, 80s, and early 90s have provided over 15 years of service.
Brochure: Biopharmaceutical Development — Bioassay Development
Bioassay development and validation are visible components of a product's path to market. The process of designing, optimizing, validating, and implementing your bioassay should be a transparent part of the biologic development cycle that fast-tracks your commercial objectives — not a bottleneck brought about by imprecise science or regulatory inexperience.
Datasheet: Endoglycosidase F2
Endoglycosidase F2 cleaves asparagine-linked or free oligomannose and biantennary complex oligosaccharides. It cleaves between the two N-acetylglucosamine residues in the diacetylchitobiose core of the oligosaccharide, generating a truncated sugar molecule with one Nacetylglucosamine residue remaining on the asparagine. In contrast, PNGase F removes the oligosaccharide intact.
Application Note: Glycolytic Enzyme Enolase
The detailed understanding of three-dimensional protein structure is important in the design of new drugs and for engineering proteins with improved properties for industrial applications.
Bulletin Board

Spectrum Chemicals and Laboratory Products launches the Fantastic Finds section of its www.SpectrumChemical.com website. Fantastic Finds is the clearance section of the website where savings of up to 80% can be found on chemicals, equipment, and supply items. Items selected for this section are either overstocked, discontinued, or nearing expiration. These specials are lot-specific and require no promotion code. Availability is subject to prior sale.

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