Evolving Toward Single-Use Bioprocessing: From Solutions To Holistic Value Creation
December 3, 2008
Feature Article: Evolving Toward Single-Use Bioprocessing: From Solutions To Holistic Value Creation
By BioProcess International
As the biopharmaceutical industry continues to evolve and mature, the challenges facing it change as well. Among many other pressures, bioprocessors are increasingly pressured to shorten drug development timelines, reduce costs, diversify product pipelines, and implement riskbased strategies, not to mention maintaining continued focus on patient safety and regulatory compliance.
Until recently, disposable technology typically meant replacing stainless steel filter housings with single-use capsules, stainless steel vessels with bags, and hard piping with flexible tubing. Other components, however, upstream and downstream of disposable solutions, often remained reusable. Intermittent use of disposables provided only intermittent solutions or benefits. This hybrid bioprocessing prevents synergistic value realization.
The bioprocessing industry is beginning to realize the full benefits that disposable technologies offer, such as faster design, construction, and validation of facilities and equipment with less capital, and the operational benefits of "flexible manufacturing." As disposables are used in more applications, they will evolve from simple solutions into a holistic value proposition for small and large biotech companies alike.
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