Articles
Evaluation Of A Metabolic Flux Model For CHO Cells To Design Highly Effective Fermentation Processes
October 1, 2009
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•Application Note: Evaluation Of A Metabolic Flux Model For CHO Cells To Design Highly Effective Fermentation Processes
•Application Note: Evaluation Of A Metabolic Flux Model For CHO Cells To Design Highly Effective Fermentation Processes
•Application Note: Evaluation Of A Metabolic Flux Model For CHO Cells To Design Highly Effective Fermentation Processes
By Jens Karschau, Michael Thiele, Susann Koch, Jens Niklas, Elmar Heinzle, Yvonne Genzel, Andreas Kremling, Udo Reichl, Uwe Marx, and René Brecht
The demand to develop highly productive processes in shortened timelines requires a shift from extensive testing procedures in bioreactor systems to a multi cell parameter analysis and intelligent prediction of optimal process design using a sophisticated model. We are in the process to develop and optimize such kind of model. This model was applied to a CHO-DG44 clone producing a monoclonal antibody for the first time.
Click Here To Download:•Application Note: Evaluation Of A Metabolic Flux Model For CHO Cells To Design Highly Effective Fermentation Processes
