Articles
Application Of Disposable Pressure Sensors To A Postcentrifugation Filtration Process
July 10, 2009
•Feature Article: Application Of Disposable Pressure Sensors To A Postcentrifugation Filtration Process
By Kevin J.R. Clark and Jim Furey
Understanding the performance of filtration unit operations in the processing of therapeutic agents is important. Incorrect or misunderstood filter performance can significantly affect the efficiency and operation of many other unit operations in a bioprocessing train. Ultimately the cost of goods will suffer significantly without adequate process characterization. Therefore, the methods and tools used to screen and size filters in a cost effective, practical, and operationally friendly manner are central to any development function. Many aspects of the wellpublicized disposable bioprocessing philosophy lend themselves particularly well to the highthroughput screening of filter types and the sizing of filters at development scales for use in scale-up models.
Reprinted with permission from BioProcess International 5(5):S44-S51 (May 2007)
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