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A Review Of Therapeutic Protein Expression By Mammalian Cells

March 26, 2010

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Article: A Review Of Therapeutic Protein Expression By Mammalian Cells

By José M. Coco-Martin and Michiel M. Harmsen

During the past five years, many biopharmaceuticals have found their way into clinical trials and commercial production. So far, about 60 million patients worldwide have benefited from these new drugs. The market for biopharmaceuticals was estimated at US$33B in 2004 and projected to reach US$70B by the end of the decade. During the period 2003–2006, regulators in Europe and the United States approved 32 biopharmaceuticals for human use, including hormones and growth factors, therapeutic enzymes, vaccines, and monoclonal antibody (MAb)-based products. An additional 1,600 biopharmaceuticals are being evaluated in clinical trials.

Reprinted with permission from BioProcess International

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Article: A Review Of Therapeutic Protein Expression By Mammalian Cells

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