Single Use Featured Articles

11. Biopharmas Increasingly Satisfied With Vendors Of Single-Use Products
    2/23/2012
    Biopharma manufacturers are increasingly satisfied with their suppliers of single-use devices, but that satisfaction is sometimes misplaced on less-critical attributes. By Eric Langer, president and managing partner, BioPlan Associates, Inc.
12. BioPharma Industry Getting Comfortable With Complex Single-Use Devices
    2/10/2012
    The rate of usage of disposables in biopharmaceutical manufacturing has increased substantially over the past six years in a variety of areas, but most notably for complex devices, that are also among the most expensive. By Eric Langer
13. Characterization Of Two Single-Use Bioreactors For Mammalian Cell Culture Processes
    2/1/2012
    Single-use cell culture bioreactors based on disposable product-contacting equipment increasingly replace established stainless steel systems. Two bioreactors were characterized towards mixing and oxygen capacity and their suitability for supporting cell growth, viability and productivity in fed-batch cultivations under chemically defined serum-free medium conditions.
14. Biopharma Manufacturers Look For Product Innovation
    1/27/2012
    Biopharma manufacturers are increasingly vocal about the new product development (NPD) areas they need to increase productivity and improve quality. By Eric Langer, president and managing partner, BioPlan Associates, Inc.
15. Continuous Processing In Bioproduction?
    1/24/2012
    In 1865 Jules Verne popularized the idea of a moon landing in From the Earth to the Moon. However, it wasn’t until over one hundred years later that technology caught up sufficiently to accomplish the feat (Apollo 11). By William G. Whitford, Sr. Market Manager, Thermo Fisher Scientific
16. New Single-Use Devices: Trends And Demands
    Single-Use Biomanufacturing Devices In High Demand
    1/5/2012
    Single-use devices are in hot demand as the biopharma industry looks for new, more innovative products. In fact, disposables make up the top 3 of 20 areas of new product development interest this year. By Eric Langer, president and managing partner, BioPlan Associates, Inc.
17. Securing Supply In Single-Use Systems — The Second-Source Decision
    11/1/2011
    The use of disposable systems for bioprocessing manufacturing has become a viable and cost-effective way for many pharmaceutical manufacturers to handle bioproduction requirements during clinical trials of drug candidates. By Wayne Koberstein
18. Demand For New Downstream Technologies Is Driving Vendors’ R&D
    10/31/2011
    Vendors are investing heavily in new technologies and products for downstream purification. Today, both developers and CMOs are expecting that physical capacity of downstream purification equipment will continue to constrain facility capacity in the near term. By Eric Langer, president and managing partner, BioPlan Associates, Inc.
19. Single Use Standards: Who’s Setting The Bar?
    9/29/2011
    Standards setting is a frequently cited stumbling block to single use systems’ (SUS) acceptance. As adoption of SUS devices advance, there is a new urgency to press for setting standards. In our 8th Annual Report and Survey of Biopharmaceutical Manufacturing, 2011, we examined who is expected to be setting disposables’ standards. By Eric Langer, president and managing partner, BioPlan Associates, Inc.
20. Applying Good Engineering Practices To The Design Of Single-Use Systems
    8/25/2011

    Significant changes are being incorporated into biopharmaceutical manufacturing processes as a result of drivers such as increasingly strict regulatory demands, reduction of manufacturing costs, and outsourcing to contract manufacturing organizations (CMOs). By Martyn Botterill and Bruce Rawlings