Single Use Featured Articles
Single-Use Equipment Standardization: Possible Or Not?
Since the introduction of single-use technologies into the biopharmaceutical processes in the early 1990s, a multitude of supplier companies mushroomed. The result is that these vendors market many unique single-use product designs, which makes it a chore for an end-user to choose and to find a second supply source. The debate is whether single-use systems can be standardized or not. It is an intense debate, as some end-users believe standardization restricts their process needs, and most vendors think that they would lose the competitive edge if they cannot customize their assemblies. By Maik W. Jornitz, Vice President, G-CON LLC
Gaining Efficiency Through Faster Integration of Single-Use Products
Considered a full-service integrator of products in the biopharmaceutical industry, Saint-Gobain offers an online platform that improves their efficiencies to design single-use products by creating a 3-dimensional product drawing.
The Benefits Of New Biopharma Products For Single-Use Systems
Meissner Filtration Products recently introduced two new products related to single-use systems – a next generation single-use mixing system and a plug-and-play filter solution. Max Blomberg, director of operations, discusses Meissner Filtration Products recently introduced two new products related to single-use systems – a next generation single-use mixing system and a plug-and-play filter solution.
What Are You Really Outsourcing When Using Single-Use Systems?
The benefits of utilizing single-use systems (SUS) within the biopharmaceutical industry are well documented in the popular press and heralded at many conferences. At a fundamental level, they present exciting and often unprecedented opportunities in terms of increased productivity, the ability to make rapid capacity adjustments and lower the overall costs of manufacturing. However, what an end-user is effectively outsourcing when they choose to include single-use assemblies within a given process step, or as the scope of their implementation broadens to include an entire process, must be considered. As single-use adoption has advanced from a curiosity to an implemented business reality for many pharmaceutical companies over the past decade, it’s relevant to explore a few key concepts that should be addressed. By Max Blomberg and Christian Julien, Meissner Filtration Products
Improved Productivity In Peptide Purification
Peptide therapeutics have been recognized as delivering the best of both worlds in terms of small molecule synthesis efficiency and biologics efficacy and reduced toxicity. However, challenges in mass production and low oral availability have historically made them less than ideal drug candidates. By Dr. Reno Nguyen, Scott Anderson, Dr. Chitra Sundararajan, Dennis McCreary and Dr. Jochen Saar
Comparison Of Air-Wheel Bioreactor Against The Traditional Stirred-Tank Bioreactor in Microcarrier Applications
A novel bioreactor system from PBS Biotech utilizes the patented Air-Wheel technology to promote uniform and homogenous liquid mixing and offers a low shear environment for cell culture.
Single-Use Budgets In 2013: Biotech Industry Council Indicates Industry Will Expand Spending On Key Products
Disposable products continue to be a hot topic in biomanufacturing, as they increasingly penetrate clinical- and commercial-stage manufacturing and are sought after for their process efficiencies. In fact, when we asked the 450 global subject matter experts and senior participants on our Biotechnology Industry Council™ to identify the critical trends in bioprocessing for 2013, 22% cited aspects associated with implementation of single-use system integration. These ranked narrowly behind need for downstream processing optimization, and analytical methods development (each at 24%). By Eric Langer, president and managing partner, BioPlan Associates, Inc.
Meeting BioPharma Needs For Lower Operating Cost And Faster Time To Market
Broad adoption awaits fully scalable GMP systems, improved and less costly disposables, better analytics, greater process automation and low-shear mixing.
Moving Ahead With Single Use Technology
This paper discusses the advantages of single-use vessel, bioreactor and mixing technologies, why they continue to grow in popularity for the bioprocessing market, and how to effectively overcome challenges in implementation of the technologies. By Richard Bhella
Budgets For Single-Use Systems On The Rise; CMOs The Biggest Spenders
Single-use systems are rapidly becoming mainstream in the biopharmaceutical industry, even in commercial manufacturing. Results from our 9th Annual Report and Survey of Biopharmaceutical Manufacturers indicate that budgets for single-use components are also on the rise, meaning this trend is likely to continue. By Eric Langer, President and Managing Partner, BioPlan Associates, Inc.