Insights On Upstream Manufacturing
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Explore A High-Performing Basal Medium And Feed Pairing
5/8/2024
A customer sought to replace a chemically defined CHO medium with a more efficient medium and feed pairing strategy in bioreactors.
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6 Key Questions When Selecting Your Cell Banking Manufacturing Partner
5/8/2024
Evaluating a potential cell banking partner's experience, testing capabilities, and approach to material management can help guarantee the quality and consistency of your therapeutic cells.
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Viral Vector Producer Cell Lines: Learning From mAbs
5/7/2024
Learn how applying bioprocessing knowledge from the production of mAbs can accelerate the development of viral vector cell lines and improve efficiency in gene therapy manufacturing.
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How To Bring (Any) mRNA To Life: Simplifying Nucleic Acid Encapsulation
5/6/2024
New technologies for the encapsulation of nucleic acids, such as FDmiX, can potentially overcome limitations of currently available standard mixing technologies.
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Review Of Applications And Processes In Fixed-Bed Bioreactors
5/6/2024
Gain insights and guidelines for developing new processes in this review evaluating publications on the applications of single-use, scalable fixed-bed bioreactors for adherent cell culture processes.
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Lentiviral Vector Production Using Single-Use Bioreactors
5/6/2024
Here, we outline a scalable and robust upstream process developed for LVV production of HEK293T cells and demonstrate how to expand HEK293T suspension cells.
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Screening Peptones, Including “Titration And Blending” Protocol Examples
5/3/2024
Dive into the importance of peptone selection, instructions for reconstituting peptone powders for mammalian cell culture, and discover starter packs containing commonly used peptones for specific applications.
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Expansion Of Specific Lymphocytes With A Xeno-Free, Serum-Free Medium
4/29/2024
Explore the advantages of utilizing a xeno- and serum-free medium for the targeted expansion of cell subpopulations without the addition of serum.
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Optimizing Perfusion Parameters Using Quality By Design
4/29/2024
In this study, the optimization of perfusion parameters to maximize CAR-T cell growth and quality within a single-use, automated stirred-tank bioreactor is systematically investigated.
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InSiliCHO: Modeling Cell Line Dynamics For Process Development
4/24/2024
Modeling and simulation can be a powerful tool for bioprocess design. Find out how you can utilize an open source implementation for in silico simulation of CHO.